Difference in ceramide composition between "dry" and "normal" skin in patients with atopic dermatitis.
نویسندگان
چکیده
Sir, Many patients with atopic dermatitis have widespread dry skin, which has a disturbed water barrier function (1). Stratum corneum lipids play an important role here. Recently, various authors have reported that dry skin in people with atopic dermatitis shows a marked reduction in ceramides (2, 3). We measured the ceramides in dry and normal skin of patients with atopic dermatitis and compared the results with those for normal individuals.
منابع مشابه
Ceramide and cholesterol composition of the skin of patients with atopic dermatitis.
Atopic dermatitis skin tends to be easily irritated and appears dry. These clinical peculiarities correspond to impaired barrier function and to increased transepidermal water loss (TEWL) values. A few studies suggest that a reduced amount of total ceramides (especially of ceramide 1) is responsible for functional abnormalities of the skin of atopic dermatitis patients. The aim of this study wa...
متن کاملClinical and virological comparison of 3 patients with erythema multiforme.
Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol 1991; 96: 523 ^ 526. 3. Di Nardo A,Wertz P, Gianetti A, Seidenari S. Ceramide and cholesterol composition of the skin of patients with atopic dermatitis. Acta Derm Venereol (Stockh) 1998; 78: 27 ^ 30. 4. Hani¢n JM, Rajka G. Diagnostic features of atopic dermatitis. Act...
متن کاملSpecific IgE to Common Food Allergens in Children with Atopic Dermatitis
Background: Atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. Although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in Iranian children with atopic dermatitis. Objectives: This study was des...
متن کاملCutaneous Leishmaniasis in Atopic Dermatitis Patients in Comparison with the Control Group in Kerman
Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in...
متن کاملAssociation of LL-37 and IL-31 serum levels with SCORing Atopic Dermatitis (SCORAD) score in atopic dermatitis patients
Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic dermatitis. Myriad pieces of evidence have pointed to the major roles of LL-37 and interleukin-31 (IL31)in atopic dermatitis. The studies on atopic dermatitis are still limited i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Acta dermato-venereologica
دوره 79 3 شماره
صفحات -
تاریخ انتشار 1999